Dermoscopy of discoid lupus erythematosus

Dermoscopy is useful in evaluating skin tumours, but its applicability expands also in the field of inflammatory skin disorders.

Discoid lupus erythematosus (DLE) represents the most common subtype of cutaneous lupus erythematosus (CLE).While dermoscopy and videodermoscopy have been shown to aid the differentiation of scalp DLE from other causes of scarring alopecia, limited data exist concerning dermoscopic criteria of DLE of other locations, such as the face, trunk and extremities.

To describe the dermoscopic criteria observed in a series of patients with DLE located elsewhere than the scalp, and to correlate them to the underlying histopathologic alterations. Methods  DLE lesions located at the face, trunk and extremities were dermoscopically and histopathologically examined. Selection of the dermoscopic variables included in the evaluation process was based on the available literature data on DLE of the scalp and our preliminary observations. Analysis of data was done with SPSS analysis software version 17.0 (SPSS Inc, Chicago, Illinois).

Fifty-five lesions from 37 patients with DLE were included in the study. Perifollicular whitish halo, follicular keratotic plugs and telangiectasias were the most common dermoscopic criteria. Statistical analysis revealed excellent correlation between dermoscopic and histopathologic findings. Notably, a time-related alteration of dermoscopic features was observed.

The present study provides new insights into the dermoscopic variability of DLE located on the face, trunk and extremities.

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mar 30 ottobre 2012
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